Difference between revisions of "IDRPublicationList"
From Clinfowiki
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== False positive == | == False positive == | ||
| + | Example of a published findings in an IDR that later turned out to be false. E.g., reporting an effect of a drug (or other findings) from an IDR analysis, but later human trials or other experiments did not validate it. | ||
* tbd | * tbd | ||
== See Also == | == See Also == | ||
* [[CIDR]] | * [[CIDR]] | ||
Revision as of 17:58, 10 April 2013
List of publications that report use of an Integrated Data Repository (IDR). ("IDR success stories")
True positive
- ROSIGLITAZONE and claims study - Nationwide, observational, retrospective, inception cohort of 227,571 Medicare beneficiaries aged 65 years or older (mean age, 74.4 years) who initiated treatment with rosiglitazone or pioglitazone through a Medicare Part D prescription drug plan from July 2006-June 2009 and who underwent follow-up for up to 3 years after thiazolidinedione initiation.
- Graham DJ et al. Risk of acute myocardial infarction, stroke, heart failure, and death in elderly Medicare patients treated with rosiglitazone or pioglitazone. JAMA doi:10.1001/jama.2010.920 http://www.ncbi.nlm.nih.gov/pubmed/20584880
- CIMETIDINE and drug repurposing. Database finding lead to a mouse model (confirmed effect) (clinical trial started [documentation missing]
- cimetidine and lung cancer http://www.ncbi.nlm.nih.gov/pubmed/21849665
- thanks to this IDR, we were able to complete this trial (anecdotal)
False positive
Example of a published findings in an IDR that later turned out to be false. E.g., reporting an effect of a drug (or other findings) from an IDR analysis, but later human trials or other experiments did not validate it.
- tbd
