Practitioners' Views on Computerized Drug—Drug Interaction Alerts in the VA System

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Adverse drug events can cause an increase in hospitalizations, deaths, and visits to the emergency department. Drug-drug interactions (DDIs) are a contributing factor to adverse drug events. This study examines the perspectives and opinions of prescribers and pharmacists about computer generated drug-drug interactions (DDIs) and their suggestions for improvement. [1]


A questionnaire was performed that asked the prescribers and pharmacists information covering DDI information, DDI alerts, DDI alert content, DDI alert burden, satisfaction with the CPOE system, sources of drug information and possible areas for improvement or modification.


61% felt that the DDI alerts had allowed them to prescribe medications safely. 30% of prescribers thought the alerts provided information they needed most of the time. As for improvements for the DDI, prescribers and pharmacists felt the system should include more detailed information as well as the alerts being accompanied by management alternatives.


Overall the prescribers and pharmacists felt the DDIs had a positive impact on their jobs and felt that it was useful. They demonstrated satisfaction with their CPOE system.


Overall there is a positive reaction to the DDI alert system within CPOE but many issues still remain such as user alert fatigue and whether these alerts are presented at the appropriate time.

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  1. Yu, 2007. Practitioners' Views on Computerized Drug—Drug Interaction Alerts in the VA System.