Effect of computerized physician order entry and a team intervention on prevention of serious medication errors

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This is a review of the study entitled Effect of Computerized Physician Order entry and a Team Intervention on Prevention of Serious Medication Errors. [1]


The objective is to evaluate the efficacy of 2 processes of interventions to find the preventing factor of adverse drug events (ADEs). ADEs can be very costly to a healthcare facility and cause serious injury.


A prevention study was conducted to evaluate two interventions. First intervention targeted the primarily the ordering stage of the medication and the second intervention targeted the administration and dispensing stages. The goal of the study was to find ways to reduce the number of preventable ADEs and no intercepted potential ADEs.


Phase 1 consisted of 2491 admission over a 6 months period include 6 units in the facility. Phase 2 consisted of 4220 admission over a 9 month period included 8 units. The patients in phase 2 consisted of minority individuals, women and older individuals (no age range was noted). The study did calculate that serious medication errors fell 55% from 10.7 events per 100 patient’s day to 4.86 events.


Medication errors are a very serious undertaking. It takes a communication from all areas of a healthcare facility and cautious medication dispersing to get control over errors.


  1. David W. Bates, MD; Lucian L. Leape, MD; David J. Cullen, MD; Nan Laird, MD; Laura A. Petersen, MD; Jonathan M. Teich, MD, PhD; Elizabeth Burdick, MS; Mairead Hickey, MD; Sharon Kleefield, MD; Brian Shea, MD; Martha Vander Vliet, RN; Diane L. Seger, RPh. JAMA. 1998;280(15):1311-1316. doi:10.1001/jama.280.15.1311. Retrieved from http://jama.jamanetwork.com/article.aspx?articleid=188074