Drug-drug interaction

When implementing drug-drug interactions, many organizations quickly realize that "Tylenol interacts with everything".

So you get a lot of alerts that fire at the “mild,” “moderate,” and “severe” level. So many organizations do a lot of tweaking of their clinical decision support early-on. For example, they turn off the “mild,” alerts after consultation with their pharmacy and therapeutics or physician review board. Then they turn off the “moderate” alerts after additional consultations. These decisions are particularly effective in hospitals with all-attending staff, where they routinely get comments from the physicians that like, “’Severe’ is all we need here.”

Missed drug-drug interactions can lead to medication errors