Difference between revisions of "Standardized Glycemic Management with a Computerized Workflow and Decision Support System for Hospitalized Patients with Type 2 Diabetes on Different Wards"

From Clinfowiki
Jump to: navigation, search
(Created page with "The following is a review of Burner et al. on the observed gender differences in diabetes self-management through the utilization of an mHealth intervention. <ref name="Burner...")
 
(Comments)
 
(11 intermediate revisions by 3 users not shown)
Line 1: Line 1:
The following is a review of Burner et al. on the observed gender differences in diabetes self-management through the utilization of an mHealth intervention. <ref name="Burner et al. 2013">Burner, E., Menchine, M., Taylor, E., & Arora, S. (2013). Gender differences in diabetes self-management: a mixed-methods analysis of a mobile health intervention for inner-city Latino patients. Journal of diabetes science and technology, 7(1), 111-118. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692222/ </ref>
+
The following is a review of Neubauer et al.(2015) study on the management of glycemic standards using computerized workflow and decision support systems. <ref name="Neubauer et al. 2015"> Neubauer, K. M., Mader, J. K., Höll, B., Aberer, F., Donsa, K., Augustin, T., ... & Pieber, T. R. (2015). Standardized glycemic management with a computerized workflow and decision support system for hospitalized patients with type 2 diabetes on different wards. Diabetes technology & therapeutics, 17(10), 685-692. http://www.ncbi.nlm.nih.gov/pubmed/26355756 </ref>
  
 
== Introduction ==
 
== Introduction ==
  
[[MHealth]] technology is an emerging field that uses devices that many patients already own and use to improve health. This promising tools have diverse features such as improving the self-management of patients suffering from chronic diseases. Diabetes has been a notorious and prominent public health problem affecting the diverse american population, especially African Americans and Hispanics. Although it has become an acclaimed tool for the implementation of follow-up treatments and self-management in patients, few is known about the factors which contribute to it's utilization such as Socio-economic status (SES). Berner et al. explore the impact of diabetes management among low-income Latino patients through the Trial to Examine Text Message for Emergency Department Patients with Diabetes (TExT-MED) a text message-based program designed to improve disease knowledge, self-efficacy, and glycemic control among low-income Latinos.
+
[[CDS]] technology is an emerging field in health informatics which combines the critical thinking of men, and optimizes it with the aid of a computerized system to yield better funded and conclusions based on evidence based medicine.The implementation tools provided by this system have promising features for physicians and their teams to arrive to optimal conclusions in the patient health delivery system. Diabetes is a well known public health issue and its management represent a greater challenge in present years. Using a paper-based algorithm for basal bolus insulin therapy developed to improve the quality of glycemic control and hospital complications, Neubauer and her team adapted it into a [[MHealth#Clinical Decision Support (CDS)|moblie decision support system]] named GlucoTab® system.
 
+
 
== Methods ==
 
== Methods ==
  
23 Diabetic patients recruited for the study were selected from the emergency department at Los Angeles County Hospital at the University of Southern California; largest public safety-net hospital in Los Angeles County serving a predominantly Latino population.
+
This study was an open, noncontrolled interventional study in hospitalized patients with Type 2 diabetes. The study was conducted on four general wards of a tertiary-care hospital: Endocrinology, Cardiology, Nephrology and Plastic Surgery. 99 hospitalized patients were recruited from 5/2013-12/2013.
  
A three-phase framework was established for the conduction of the study:
+
GlucoTab® system applied a daily dose of basal insulin, bolus insulin before each meal, and a correctional dose at bedtime to achieve fasting and premeal BG (Blood Glucose) values of less than 140 mg/dL. One-half of the total daily dose was administered as basal insulin once a day before lunch. The other half was administered as bolus insulin three times a day (45% of the total dose for breakfast bolus, 25% for lunch bolus, and 30% for dinner bolus).
  
* Phase I (Completed, May 2011) - Tested feasibility and acceptability among the target population.  
+
* Daily dose: 0.5 units/kg
- 1-month bilingual (English and Spanish) diabetes curriculum of text messages
+
- Three messages/day in preferred language: (1) educational and motivational messages (67%), (2) trivia questions (12%), (3) healthy-behavior challenge (14%)
+
  
* Phase II (The study) -  Qualitative analysis of the program.
+
In order to yield the results from the study the following procedures were conducted:
- Assembled two focus groups of 90-min duration—one in English and one in Spanish from the pool of Phase I participants. Moderator delivered consistent probes between groups.
+
- Including:  (1) how they sought health information, (2) how trustworthy and valid they found the information from TExT-MED, (3) whether they sought further information after receiving a text message, and (4) with whom they shared the TExT-MED information.
+
- Conversations were recorded and transcribed for further analysis.
+
  
* Phase III (Ongoing) - Randomized and Controlled trials.
+
* To test if the mean percentage of BG measurements in the target range 70–140 mg/dL were greater than the ones in the recent best-practice study with the criterion value of 42%, they applied a one-tailed one-sample t test. <ref name="Umpierrez et al. 2013"> Umpierrez GE, Smiley D, Hermayer K, et al.: Randomized study comparing a basal-bolus with a basal plus correction insulin regimen for the hospital management of medical and surgical patients with type 2 diabetes: basal plus trial. Diabetes Care 2013;36:2169–2174 </ref>
  
== Results == 
+
* The wards were compared using the Kruskal–Wallis rank sum test for secondary outcome since patients were unequally distributed among the wards.
  
* Phase I - 20 patients were able to follow-up for data collection at trial completion.
+
*Finally, a multiple regression model to predict the mean daily BG value over all study days, except study Day 1, was fitted to the data.
- Men’s average scores on the Diabetes Knowledge Questionnaire decreased slightly (8.4 to 6.8), while women’s knowledge increased (8.5 to 10.5).  
+
  
- Self-efficacy measured by the Diabetes Empowerment Scale improved for men, with a minimal change for women (30 to 33.4 for men and 34.2 to 34.0 for women).
+
== Results == 
  
- Checking food labels did not change for men or women, while percent of patients who ate a fruit or vegetable each day improved for men (from 43% to 82%) but did not change for women.  
+
* GlucoTab® system was highly accepted; Physicians adhered to the suggested total daily insulin doses in 97.5% of cases, and nurses' adherence rates with suggested bolus insulin doses and basal insulin doses were 96.5% and 96.7%
  
- Medication adherence and exercise behaviors improved for both gender groups.  
+
* The mean percentage of BG measurements in the target range 70–140 mg/dL was 50.2±22.2%; Higher than the criterion value of 42% derived from the recent best-practice study
  
- Women increased the number of times they checked their blood sugar and feet, while men exhibited no change in blood sugar checks and decreased the number of times they checked their feet.
+
* Twenty-eight mild and moderate adverse events and one serious adverse event occurred, nonetheless not a single one was attributed to the GlucoTab® system
 
+
* Phase II - 8 patients returned for focus groups
+
 
+
From the qualitative analysis three major factors were identified as prominent differences between genders:
+
 
+
(1) Dietary self-efficacy
+
- Male subjects felt that their knowledge on diet and ability to prepare their own meals, affected their self-management of diabetes.
+
 
+
(2) Health information sources
+
- Males: Mainly obtained their knowledge either from physicians or media (TV, radio, internet)
+
- Females: Mainly obtained their knowledge from family or fiends advises
+
 
+
(3) Desired content of further educational materials
+
- Males: Erectile dysfunction was a prominent topic among all of them
+
- Females: Prevention of yeast infection and menopause
+
  
 +
* GlucoTab® system received positive feedback through a questionnaire from 59 of 65 physicians
 +
 
 
== Conclusion ==
 
== Conclusion ==
  
Analysis through the TExT-MED shows that low-income Latino patients will accept text messages as a behavioral intervention. This mHealth intervention acts as a behavioral trigger rather than an education platform. Although the sample size in this study is low, we shouldn't consider it a failure. The work conducted in the study by Burner et al. shows that indeed perzonalization would be a task required in mHealth if further improvement of self-management of diabetes and chronic diseases wants to observed.
+
The GlucoTab® system can be implemented in the clinical setting according to the results yield by the study. Factors such as preexisting home insulin therapy and the HbA1c values in addition to the type of hospital admission and the first total daily insulin dose can be pointed as the cause for the high BG mean values yielded during hospitalization. Inclusion criteria of the patients as them been non-controlled and open, represent a serious implication to asses the results as reliable.
  
 
== Comments ==  
 
== Comments ==  
Proper education and management of chronic diseases such as diabetes is important to improve quality of life.  The search for innovative, accessible and cost effective tools is essential for patients of all ethnic groups. mHealth is a technology that will benefit many patients.
+
GlucoTab® system allowed an efficient, safe, and friendly-user implementation of a standardized glycemic management system throughout the different wards of the hospital. Data in such study further only supports the claim that systems such as this can improve the health care delivery of diabetes with confidence of not expecting consequences due to their implementation. This study not only highlights the fact that if a CDS tool is implemented properly can have a positive impact in clinical outcomes but also become a powerful teaching tool for the physicians in training.
 +
 
 +
== Related Articles ==
 +
*[[Benefits of Information Technology-Enabled Diabetes Management]]
 +
*[[Impact of electronic health record clinical decision support on diabetes care: a randomized trial]]
  
 
== References ==
 
== References ==
Line 62: Line 47:
  
 
[[Category:Reviews]]
 
[[Category:Reviews]]
 +
[[Category:CDS]]
 
[[Category:MHealth]]
 
[[Category:MHealth]]

Latest revision as of 22:14, 18 October 2015

The following is a review of Neubauer et al.(2015) study on the management of glycemic standards using computerized workflow and decision support systems. [1]

Introduction

CDS technology is an emerging field in health informatics which combines the critical thinking of men, and optimizes it with the aid of a computerized system to yield better funded and conclusions based on evidence based medicine.The implementation tools provided by this system have promising features for physicians and their teams to arrive to optimal conclusions in the patient health delivery system. Diabetes is a well known public health issue and its management represent a greater challenge in present years. Using a paper-based algorithm for basal bolus insulin therapy developed to improve the quality of glycemic control and hospital complications, Neubauer and her team adapted it into a moblie decision support system named GlucoTab® system.

Methods

This study was an open, noncontrolled interventional study in hospitalized patients with Type 2 diabetes. The study was conducted on four general wards of a tertiary-care hospital: Endocrinology, Cardiology, Nephrology and Plastic Surgery. 99 hospitalized patients were recruited from 5/2013-12/2013.

GlucoTab® system applied a daily dose of basal insulin, bolus insulin before each meal, and a correctional dose at bedtime to achieve fasting and premeal BG (Blood Glucose) values of less than 140 mg/dL. One-half of the total daily dose was administered as basal insulin once a day before lunch. The other half was administered as bolus insulin three times a day (45% of the total dose for breakfast bolus, 25% for lunch bolus, and 30% for dinner bolus).

  • Daily dose: 0.5 units/kg

In order to yield the results from the study the following procedures were conducted:

  • To test if the mean percentage of BG measurements in the target range 70–140 mg/dL were greater than the ones in the recent best-practice study with the criterion value of 42%, they applied a one-tailed one-sample t test. [2]
  • The wards were compared using the Kruskal–Wallis rank sum test for secondary outcome since patients were unequally distributed among the wards.
  • Finally, a multiple regression model to predict the mean daily BG value over all study days, except study Day 1, was fitted to the data.

Results

  • GlucoTab® system was highly accepted; Physicians adhered to the suggested total daily insulin doses in 97.5% of cases, and nurses' adherence rates with suggested bolus insulin doses and basal insulin doses were 96.5% and 96.7%
  • The mean percentage of BG measurements in the target range 70–140 mg/dL was 50.2±22.2%; Higher than the criterion value of 42% derived from the recent best-practice study
  • Twenty-eight mild and moderate adverse events and one serious adverse event occurred, nonetheless not a single one was attributed to the GlucoTab® system
  • GlucoTab® system received positive feedback through a questionnaire from 59 of 65 physicians

Conclusion

The GlucoTab® system can be implemented in the clinical setting according to the results yield by the study. Factors such as preexisting home insulin therapy and the HbA1c values in addition to the type of hospital admission and the first total daily insulin dose can be pointed as the cause for the high BG mean values yielded during hospitalization. Inclusion criteria of the patients as them been non-controlled and open, represent a serious implication to asses the results as reliable.

Comments

GlucoTab® system allowed an efficient, safe, and friendly-user implementation of a standardized glycemic management system throughout the different wards of the hospital. Data in such study further only supports the claim that systems such as this can improve the health care delivery of diabetes with confidence of not expecting consequences due to their implementation. This study not only highlights the fact that if a CDS tool is implemented properly can have a positive impact in clinical outcomes but also become a powerful teaching tool for the physicians in training.

Related Articles

References

  1. Neubauer, K. M., Mader, J. K., Höll, B., Aberer, F., Donsa, K., Augustin, T., ... & Pieber, T. R. (2015). Standardized glycemic management with a computerized workflow and decision support system for hospitalized patients with type 2 diabetes on different wards. Diabetes technology & therapeutics, 17(10), 685-692. http://www.ncbi.nlm.nih.gov/pubmed/26355756
  2. Umpierrez GE, Smiley D, Hermayer K, et al.: Randomized study comparing a basal-bolus with a basal plus correction insulin regimen for the hospital management of medical and surgical patients with type 2 diabetes: basal plus trial. Diabetes Care 2013;36:2169–2174