Vaccination contraindications

From Clinfowiki
Jump to: navigation, search

Prior to administration of vaccinations of children and adults, patients need be screened for potential contraindications and precautions. Allergies and conditions which predispose individuals to immunocompromise represent a large proportion of these contraindications. To minimize risk from vaccine administration, the Centers for Disease Control and Prevention (CDC) have released a report which delineates such situations.

Situations that may warrant precautions or contraindications to vaccine administration

  • Anaphylactic allergies
    • (e.g., allergies to eggs (influenza))
  • Anaphylactic reaction to previous dose of any vaccine
  • Anthrax (prior infection)
  • Antimicrobial therapy (current)
  • Eczema or atopic dermatitis in patient or household contact
  • Guillian-Barré Syndrome, history of
  • Hematopoietic stem cell transplant
  • HIV (in recipient)
  • Immune globulin (IG) administration, recent
  • Illness (moderate to severe acute illness, fever, otitis, diarrhea, vomiting)
  • Immunodeficiency:
    • Family history
    • In household contact
    • In recipient
  • Neurologic disorder
  • Pregnancy:
    • In mother or household contact of recipient
    • In recipient
  • Reaction to previous vaccine dose
  • Skin condition (acute, chronic or exfoliative)
  • Thrombocytopenic purpura


The CDC Contraindication and Vaccine Guide [1]

Contraindications by vaccine are also available. [2]

Atkinson WL, et al. General Recommendations on Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP) and the American Academy of Family Physicians (AAFP). MMWR Feb 8 2002; 51(RR02):1-36[3]